LubriSyn and hyaluron
Does anyone on this list have experience with Lubrisyn?
http://www.lubrisyn.com/about/
"LubriSyn™ is a patented, daily supplement of hyaluronic acid (HA),
which occurs naturally in healthy tissue. HA is the main component of
the synovial fluid that cushions equine joints, so two adjacent
cartilage caps glide against each other with minimal friction"
Thanks Deb
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Although I can't speak to equine use, the cool thing about hyaluronic acid in human medicine is that it isn't technically a drug in that it's effect is not achieved through chemical action or by being metabolized by the body. It's a polymer, albeit a natural constituent of synovial fluid and cartilage. So, FDA hyaluronic acid products are approved through CDRH (first in 1997) as a device - not a drug. http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfPMA/PMA.cfm?ID=6926
Despite widespread use and acceptance by the medical community, a re-evaluation of the published clinical evidence by the BCBSA TEC in 2005 concludes:
"...hyaluronan (injected into the knee for painful osteoarthritis) is about as roughly as effective as NSAIDs. However, this literature base remains small, and the quality of the evidence is not very good."
http://www.bcbs.com/betterknowledge/tec/vols/19/19_17.pdf
Products containing hyaluronic acid have been used as an injection since the early 80's to lubricate the painful osteoarthritic knee. Made primarily from chicken combs, sodium hyaluronate (hyaluronic acid) injection products now have FDA PMA approvals for ophthalmologic use in cataract surgery, and injection into the mid to deep dermis for correction of moderate wrinkles.
Anywho, let's think about this. Would a non-bioactive substance consumed into the digestive tract somehow find it's way, and to a significant degree, into the articular spaces of painful joints? AND, would that orally consumed substance, if it made it's way to the joints, result in an appreciable difference in symptoms? Maybe, but what does that say about eating Elmer's Glue (no equine pun intended), swallowing chewing-gum, or using Tupperware?
BTW. MEDLINE identifies no human studies using oral hyalonurate containing substances.
-nawledge
http://www.lubrisyn.com/about/
"LubriSyn™ is a patented, daily supplement of hyaluronic acid (HA),
which occurs naturally in healthy tissue. HA is the main component of
the synovial fluid that cushions equine joints, so two adjacent
cartilage caps glide against each other with minimal friction"
Thanks Deb
<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<
Although I can't speak to equine use, the cool thing about hyaluronic acid in human medicine is that it isn't technically a drug in that it's effect is not achieved through chemical action or by being metabolized by the body. It's a polymer, albeit a natural constituent of synovial fluid and cartilage. So, FDA hyaluronic acid products are approved through CDRH (first in 1997) as a device - not a drug. http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfPMA/PMA.cfm?ID=6926
Despite widespread use and acceptance by the medical community, a re-evaluation of the published clinical evidence by the BCBSA TEC in 2005 concludes:
"...hyaluronan (injected into the knee for painful osteoarthritis) is about as roughly as effective as NSAIDs. However, this literature base remains small, and the quality of the evidence is not very good."
http://www.bcbs.com/betterknowledge/tec/vols/19/19_17.pdf
Products containing hyaluronic acid have been used as an injection since the early 80's to lubricate the painful osteoarthritic knee. Made primarily from chicken combs, sodium hyaluronate (hyaluronic acid) injection products now have FDA PMA approvals for ophthalmologic use in cataract surgery, and injection into the mid to deep dermis for correction of moderate wrinkles.
Anywho, let's think about this. Would a non-bioactive substance consumed into the digestive tract somehow find it's way, and to a significant degree, into the articular spaces of painful joints? AND, would that orally consumed substance, if it made it's way to the joints, result in an appreciable difference in symptoms? Maybe, but what does that say about eating Elmer's Glue (no equine pun intended), swallowing chewing-gum, or using Tupperware?
BTW. MEDLINE identifies no human studies using oral hyalonurate containing substances.
-nawledge
posted by nawledge at
9:48 PM
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