dras knowledge

Friday, March 30, 2007

NATURE helps explain how Homeopathy is Different

The article presents the homeopaths argument that the emphasis homeopaths place on individually tailored treatment makes designing double-blind, placebo-controlled trials a challenge. But, that the homeopathy remedy itself does have an effect independent of the practitioner.

From the article:http://www.nature.com/news/2007/070319/full/446352a.html

"...Clare Relton, a practising homeopath who is conducting research into homeopathy at the University of Sheffield and has taken part in a clinical trial designed to assess homeopathic treatments for chronic fatigue syndrome. "I found it difficult to build a therapeutic relationship," she says. Relton argues that homeopathy is scientific, but that the problem of trust means that double-blind trials aren't the best way to measure its effectiveness..."

IOW, the patient and the homeopath have to believe in the treatment or it won't work. So, in study, we can't blind the homeopaths as to whether their remedies are true or placebo, because a doubt (by either patient or practitioner) as to whether they have a real remedy will negatively influence the treatment outcome.

"...Instead, she and other homeopaths prefer to rely on more qualitative methods, such as case studies and non-blinded comparisons of treatment options. These, they say, provide ample evidence that homeopathy works."

"Qualitative methods" probably means they cherry-pick those higher-quality cases where the patient, practitioner, and remedy clicked right-along from the get-go, and the patient got better. "Study" probably then consists of discerning how to make every case click-right-along like these more successful cases.

This should all make sense now. It doesn't matter that not one active substance molecule remains in the homeopathic remedy. We only need to know that the remedy once had an association with the active substance. And then we need only create that same kind of true connection between the remedy, the practitioner, and the patients infirmity. The belief and the positive conviction and emotion are the key to success in Homeopathy.

But, wait. Does then the Homeopathic remedy become a mere talisman? And its use mere ritual? If that is the case, we in evidence-based science are trying to compare the apples of Homeopathy with the oranges of EBM. We perhaps should rather compare homeopathy with other methods of healing that use or require talismans and rituals.

Alternately, we will have to breech or skirt our ethics for clinical study and double-blind both the practitioner and patient in that neither one knows they are in a study and assigned to either active treatment or placebo. If we do this, I predict that, as in the study comparing acupuncture and sham-acupuncture, both study arms will produce a positive effect and the WHO will herald Homeopathy as effective.

-n

Tuesday, March 27, 2007

Trafficker or Healer? MD's and Pain Meds

This case is particularly relevant to those in health fraud concerned with prescription drug abuse (my home state of Utah being the current per-capita national champion). The outcome will effect how much liability the prescribing physicians have. The article expresses the point that doctors can't be detectives, and should never be afraid of DEA inquiry every time a narcotics prescription is written. There's the need to protect a physician in the practice of medicine, and there's also a need to prevent intentional MD traffickers from abusing then hiding behind their title.

-N

"Dr. Hurwitz, depending on which side you listen to, is either the most infamous doctor-turned-drug-trafficker in America or a compassionate physician being persecuted because a few patients duped him.
When Dr. Hurwitz, who is now 62, was sent to prison in 2004 for 25 years on drug trafficking and other charges,...

http://www.nytimes.com/2007/03/27/science/27tier.html?_r=1&ref=health&oref=slogin

Trafficker or Healer? And Who’s the Victim?

By JOHN TIERNEY
Published: March 27, 2007
ALEXANDRIA, Va., March 26 —

Thursday, March 22, 2007

There is no "Autism Epidemic"

>There are 2 hypothesis:
>
>A: There is a report that autism now affects 1 child in every
>150. (This one is based on solid data)
>B: Autism is not on increase, but we just have different diagnostic
>criteria adding more people to Autism Spectrum (are there any data
>supporting this one?)
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I know there has been much said in support of the Hypothesis B. Right off the top of my head, here is the study published last july in Pediatrics

http://pediatrics.aappublications.org/cgi/content/full/118/1/e139?maxtoshow=
Fombonne E, Zakarian R, Bennett A, Meng L,
McLean-Heywood D. Pervasive developmental disorders in
Montreal, Quebec, Canada: prevalence and links with
immunizations. Pediatrics. 2006 Jul;118(1):e139-50.
PMID: 16818529
CONCLUSIONS. The prevalence of pervasive developmental disorder in Montreal was high, increasing in recent birth cohorts as found in most countries. Factors accounting for the increase include a broadening of diagnostic concepts and criteria, increased awareness and, therefore, better identification of children with pervasive developmental disorders in communities and epidemiologic surveys, and improved access to services. The findings ruled out an association between pervasive developmental disorder and either high levels of ethylmercury exposure comparable with those experienced in the United States in the 1990s or 1- or 2-dose measles-mumps-rubella vaccinations.


------------------------
>If one out of 150 people have Autism Spectrum, then one out of 5
>people should have an Autistic ancestor/relative in the first 3 generations.
>I have none. I have many friends. None again.
-------------------------


[N-] How do you know that? Have all 150 adult relatives been evaluated or even screened for Autism Spectrum by a current qualified behavioral health professional? And, who's to say that children with some attributes of autism spectrum don't learn to capably interact with their surroundings by the time they are adults, and don't overly or openly express Autism Spectrum tendencies?

--------------------------
>How many here have a photo of a relative who would
>fit diagnosis of "Autism Spectrum", but was, at the time, considered
>a "retard", "mentally sick", "stupid
>idot", "strange", "antisocial", .... "lack the ability to
>spontaneously develop effective social interaction skills"
>or whatever else could have been names for Autism Spectrum people in the past?
>I never heard about an 80 years old grandma who would fit "Autism Spectrum" ?
----------------------------

[N-] Because they are family, and genetically and/or environmentally connected, do you suppose you may carry bias in self-analyzing your own relatives as fitting definitions described above? Nevertheless, I hear people call their in-laws these names all the time. (Not me, boy!) Looking at an unrelated population, get to know just the few dozen people you work with and then start "looking" for autistic-like behavior around you at work. Is there one out of 150 people that jump out at you? (In my case, it's more like one out of twelve - or maybe it's just me.) I'm still open-minded on this (or any) issue and would appreciate more discussion. But, so far, I'm not convinced of an Autism Epidemic.

Wednesday, March 21, 2007

Medical "News" in the Olympian

http://www.theolympian.com/105/v-print/story/71163.html

- Doctor explains the myths of digestion -

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The reporter states that:

"After I interviewed Dr. Wright, I became confident that I did suffer from low stomach acid myself "

But the reporter just finished saying that, per Dr. Wright, one should get "tested by a qualified health practitioner - rather than just assume that your problem is caused by low stomach acid."

It doesn't seem proper that a supposedly unbiased reporter so wholeheartedly supports Dr. Wright's "philosophies", especially when the article admits that they are controversial. This report reads like a marketing tract for nutritional supplements. Nevertheless, it stands as perhaps unethical for the article to address seniors with an apparent attempt to convince them that they need testing, and likely need supplements. Our seniors deserve true, unbiased, and especially meaningful health information, not a subtle attempt to scare or otherwise convince them to seek unestablished testing and supplement recommendations.

The statement that, "This isn't alternative medicine,” contradicts the earlier statements in the article suggesting that all of traditional medicine is wrong about too much stomach acid. Nevertheless, if this is not alternative medicine, then it is something worse: pseudoscience.

I challenge The Olympian to raise it's level of journalistic integrity and be accountable to it, especially with health information directed toward seniors.

(my posted letter to the editor)

Additionally,

In the case of this reporter, it takes little research to speculate that, with her(?) absence of other symptoms, and if she is over 60 years old, she would likely be inexpensively tested by the Tahoma clinic and conclusively diagnosed with low acid. And sold into a relatively inexpensive HCL/Pepsid supplements regimen, in accordance with her budget. To speculate further, if she's under 60 years old, but over 45, her stomach acid test will likely be inconclusive, and eventually, perhaps natural hormone replacement therapy will be prescribed for her signs and symptoms. This is based on the topic of another of Dr. Wright's books.

Many will call Dr. Wright's presentation pseudoscience. There's enough scientific legitimacy surrounding the vagueness in good pseudoscience that it's hard to find any details that can be empirically refuted by other medical professionals. For example, there is no common way to describe or measure body "vibrancy," or to medically describe or define the terms "good quality cells" and "age faster." There is also ample good science and traditional medical understanding in the presentation. However, note that it is mostly background information that doesn't actually support all the "philosophy" about low stomach acid, and is otherwise used in the presentation to create sensation, fear, familiarity, and authority. The only statement left in this message that really is a medical claim is that, a cheap test can diagnose low stomach acid, which can cause health symptoms. It is plainly obvious that much more information is attached, suggested, or otherwise inferred that can be
readily disputed. For example, I get an understanding from the article that high stomach acid is not a source for symptoms, that older people need testing and supplements, and that grave health consequences result in the absence of testing and supplements. But none of this is actually stated, is it?

My advice to the reporter is to persist with attempts at contacting the gastroenterology society, and get that second opinion.

-N

>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>

Thursday, March 15, 2007

More on Autism and Vaccines ("Pediatrics" study)

http://www.medicalnewstoday.com/medicalnews.php?newsid=64733

________________________________________________


The linked article is a report of a presentation given at a "National Autism Association meeting." The presentation is about a "study" the authors did that reportedly specifically refutes conclusions of a prior autism study published in Pediatrics. This press report of the presentation really sounds like the presentation was more about attacking the Pediatrics study than it was about presenting the new data. We have to wait for the author to peer-review-publish his study findings before we can take what he says in a presentation with much legitimacy. This is especially true in being that this is an emotionally charged issue.

-N

Personalized Health Care Initiative Endorsed by US Govt.

http://www.hhs.gov/myhealthcare/

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[N-]

From the linked HHS website:

"The Personalized Health Care Initiative will improve the safety, quality and effectiveness of healthcare for every patient in the US. By using “genomics”, or the identification of genes and how they relate to drug treatment, personalized health care will enable medicine to be tailored to each person’s needs."

The description of this initiative is a little disturbing. I am not within the inner circles of gemonics research, but I am not ignorant either, and have followed much in the practical clinical utility of genetic studies in its application to ameliorate human disease. And, frankly, don't suspect that a broad ("every patient"?) application of genomics will be plausible anywhere in the near future. Is this Mr. Bush's Reagan-esk "Star Wars" SDI solution to this generation's biggest fear? Problem is, Reagan only had to be right-enough about the plausibility of SDI to contribute to a solution to the Cold War, by pulling one over on the USSR. If Mr. Bush isn't right-enough about the plausibility of "genomics" in contributing to a solution to the nation's health care crisis, we are worse off than before.

On the one hand, we politically restrict government funding associated with stem cells on ethical grounds, while on the other, open the federal dollar flood gates for something called "genomics." Personally, I find the idea of my complete genetic make-up sitting in a federal database just as ethically disturbing as the idea of my progeny stem cells cooking in a government funded test tube.

Nawledge

Wednesday, March 14, 2007

NCCAM New Research Concept

New Research Concept:

Omics and Variable Responses to CAM: Secondary Analysis of
CAM Clinical Trials
This initiative is intended to leverage NCCAM's investment
in ongoing and completed clinical trials through
examination of differences in genomics, proteomics, and
metabolomics that may be responsible for variations in
individual responses to CAM interventions. The concept was
approved at the February 2, 2007 meeting of the NCCAM
Advisory Council Meeting and will be
developed into a future funding opportunity.

URL: http://nccam.nih.gov/research/concepts/consider/omics.htm

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So, when I go into see my herbalist, I'll be recommended for genetic testing to find out which all-natural liver detoxifier will work for me.

Oh, and doesn't this initiative really play into the "clinical studies don't work because everyone is different" CAM philosophy.

And, BTW, NCCAM will need resources to pour over all those (apparently) negative CAM studies in order to find out this (predicted) real reason why the treatments didn't work.

In breaking down genes to look for reasons for individual variability in responses to CAM treatment, maybe they could also look for genetic correlation to an individuals psychological makeup or personal belief structure?

nawledge (In a lapsing fit of cynicism)

Thursday, March 01, 2007

Big Pharm conspiracy turn-around

http://www.gazettetimes.com/articles/2007/02/28/news/community/5loc02_vitamin.txt



...."Prescribing drugs is an easy way for doctors to address patients' health problems, Frei said, and the pharmaceutical industry is very lucrative. There's less money and more work involved in preventing illness by encouraging a healthy lifestyle...

"...While antioxidants can't undo the damage caused by a lifetime of smoking or other risky behaviors, they can help prevent disease when combined with a healthy diet and lifestyle..."

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It could just as is easily be said that:

..."Recommending dietary supplements is an easy way for CAM practitioners to address patient's health concerns, and the Nutri-ceutical industry is very lucrative. There's less money and more work involved in preventing illness by encouraging a healthy lifestyle....

"While antioxidants can't undo the damage caused by a lifetime of smoking or other risky behaviors, a healthy diet and lifestyle can help prevent disease, and it's a fallacy that taking supplements goes hand-in-hand with diet and a healthy lifestyle."

-nawledge